Role of extracellular vesicles in intercellular and interorgan communication in diabetic nephropathy
10.3760/cma.j.cn441217-20231222-01241
- VernacularTitle:细胞外囊泡在糖尿病肾病细胞间与器官间的通信作用
- Author:
Qin LAN
1
;
Hongyan LONG
;
Jingjing DA
;
Fuxun YU
;
Yan ZHA
Author Information
1. 遵义医科大学研究生院,遵义 563099
- Publication Type:Journal Article
- Keywords:
Extracellular vesicles;
Diabetic nephropathies;
Intercellular crosstalk;
Interorgan crosstalk
- From:
Chinese Journal of Nephrology
2024;40(12):984-989
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles (EVs) are communication vectors between cells and organs, which have been demonstrated new potential role in the pathogenesis, diagnosis, and treatment of kidney diseases. This paper describes the role of EVs in intercellular and inter organ communication in diabetic nephropathy by reviewing the biological properties of EVs, EVs-mediated organ-organ crosstalk, cell-cell crosstalk in diabetic nephropathy, and the role of EVs in the diagnosis and treatment of renal diseases. These insights aim to provide a theoretical basis for a more comprehensive understanding of the role of EVs in the pathogenesis and progression of diabetic nephropathy.