Recent advances in small molecule drugs for inflammatory bowel disease
10.3760/cma.j.cn101480-20230117-00007
- VernacularTitle:小分子药物治疗炎症性肠病的最新研究进展
- Author:
Dongying YAO
1
;
Zhihua RAN
1
Author Information
1. 上海健康医学院附属周浦医院消化科 201318
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Small molecule drugs;
Janus kinase inhibitor;
Sphingosine-1-phosphate agonists
- From:
Chinese Journal of Inflammatory Bowel Diseases
2023;07(2):119-123
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease is a chronic non-specific intestinal inflammatory disease. Biological agents have good clinical efficacy, but some patients may stop treatment due to adverse reactions. New oral small molecule drugs have the characteristics of small molecular weight, easier passage through cell membrane and short half-life, and have good curative effect on IBD. This article reviews the research progress of small molecule drugs for the treatment of IBD, in order to guide clinical application.