A case report of chronic kidney disease-associated pruritus treated by nalfurafine hydrochloride
10.3760/cma.j.cn441217-20240909-00917
- VernacularTitle:盐酸纳呋拉啡治疗慢性肾脏病相关瘙痒症1例
- Author:
Nan ZHU
1
;
Xin WANG
1
;
Lili YANG
1
;
Fangxing ZHANG
1
;
Pei WANG
1
Author Information
1. 郑州大学第一附属医院血液净化中心，郑州 450052
- Publication Type:Journal Article
- Keywords:
Pruritus;
Renal dialysis;
Drug therapy;
Nalfurafine hydrochloride
- From:
Chinese Journal of Nephrology
2025;41(3):205-208
- CountryChina
- Language:Chinese
-
Abstract:
Pruritus is one of the common comorbidities in patients with chronic kidney disease, significantly reducing life quality and increasing the risks of depression and mortality. This report presents the treatment process of a patient undergoing maintenance hemodialysis with pruritus. The patient successively received an optimized dialysis prescription, management of chronic kidney disease-related mineral and bone disorder, correction of secondary hyperparathyroidism, enhanced skin care, and administration of gabapentin. However, pruritus symptoms of this patient persisted. Subsequently, the patient was treated with nalfurafine hydrochloride, resulting in significant relief of pruritus symptoms without any adverse reaction. This case provides new insights and references for the treatment of chronic kidney disease-associated pruritus.
