Research progress of intestinal lymphatic system dysfunction in Crohn′s disease
10.3760/cma.j.cn101480-20220328-00053
- VernacularTitle:克罗恩病肠淋巴系统功能障碍的研究进展
- Author:
Hui LU
1
;
Quanli LIU
;
Li SHEN
;
Ruohan SHI
;
Mengyu XU
;
Lugen ZUO
;
Zhijun GENG
Author Information
1. 蚌埠医学院，蚌埠 233030
- Publication Type:Journal Article
- Keywords:
Crohn′s disease;
Intestinal lymphatic system;
Lymphatic vessel
- From:
Chinese Journal of Inflammatory Bowel Diseases
2023;07(2):191-194
- CountryChina
- Language:Chinese
-
Abstract:
Crohn′s disease (CD) is a complex gastrointestinal tract disease, and its etiology and pathogenesis have not been fully clarified. In recent years, studies on the intestinal lymphatic system in CD patients have gradually increased. Dysfunction of the intestinal lymphatic system is often seen in the development and progression of CD and affects the disease process, such as lymphogranuloma formation, lymphatic dilation and lymphatic leakage, and its dysfunction is often associated with pathological features of CD patients such as creeping fat and segmental enterocolitis. This review summarizes recent studies related to the dysfunction of the intestinal lymphatic system in CD, and describes the possible effects of the dysfunction of the intestinal lymphatic system on CD by linking the dysfunctional manifestations of lymphatic function to the pathological manifestations of CD.
