Ultrasound evaluation of transmural healing in Crohn′s disease: methods and values
10.3760/cma.j.cn101480-20220914-00147
- VernacularTitle:克罗恩病透壁愈合的超声评估方法和价值
- Author:
Wenjie CHENG
1
;
Si QIN
;
Zhuohua LIANG
;
Guangjian LIU
Author Information
1. 中山大学附属第六医院超声科，广州 510655
- Publication Type:Journal Article
- Keywords:
Crohn′s disease;
Transmural healing;
Intestinal ultrasound;
Bowel wall thickness;
Color doppler signal
- From:
Chinese Journal of Inflammatory Bowel Diseases
2023;07(1):27-31
- CountryChina
- Language:Chinese
-
Abstract:
With the progress of disease diagnosis and treatment, the treatment goals of Crohn′s disease have evolved from clinical remission to mucosal healing, and ultimately towards transmural healing. Accumulating evidence suggests a good association between transmural healing and a better long-term outcome. However, the definition and evaluation criteria of transmural healing reported in literatures are not uniform at present. The bowel wall thickness ≤3 mm with or without normal color doppler signal assessed by doppler ultrasound is regarded as the criterion of transmural healing in most of studies. Although other parameters of conventional ultrasound (bowel wall stratification and inflammatory mesenteric fat) and new ultrasound techniques (contrast enhanced ultrasound and ultrasound elastic imaging) are related to inflammatory activity to a certain extent, there is no sufficient evidence to prove their value in evaluating transmural healing. We suggest that normal bowel wall thickness and bowel wall flow should be used as the criteria for evaluating transmural healing.
