Factors influencing quality of life in patients with inflammatory bowel disease
10.3760/cma.j.cn101480-20220523-00074
- VernacularTitle:炎症性肠病患者生活质量的影响因素分析
- Author:
Jun LIU
1
;
Jie LIU
1
;
Xuejuan CHEN
1
;
Xianmin XUE
1
;
Xiaoning LI
1
Author Information
1. 空军军医大学第一附属医院消化内科，西安 710032
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Quality of life;
Disease acceptance;
Disease activity;
Influencing factors
- From:
Chinese Journal of Inflammatory Bowel Diseases
2022;06(4):330-334
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the influencing factors of quality of life in patients with inflammatory bowel disease (IBD) , especially the effect of disease acceptance on quality of life.Methods:A cross-sectional study was conducted to select 244 IBD patients diagnosed in the First Affiliated Hospital of Air Force Medical University from January to October 2020 by convenience sampling. The general information questionnaire, Chinese version of illness acceptance scale (AIS-CHI) and inflammatory bowel disease quality of life (IBDQ) were used to collect the data of patients. Univariate analysis was used to compare the differences of quality of life in IBD patients with different characteristics. Factors with statistical significance in univariate analysis were included in multiple linear regression analysis to determine the independent influencing factors. Pearson correlation was used to analyze the correlation between quality of life and disease acceptance in IBD patients.Results:The quality of life score of IBD patients was (173.71 ± 33.52) points, which was at a low level. The disease acceptance score was (22.32 ± 7.34) points, which was at a moderate and low level. Univariate analysis showed that there were significant differences in quality of life score between the patients with different education levels, personalities, monthly incomes, acceptances of disease and disease activities (all P<0.05) . Multiple linear regression analysis showed that disease acceptance and disease activity were independent influencing factors of quality of life. Disease acceptance was positively correlated with the quality of life ( b = 2.625, t = 10.477, P<0.001) , and disease activity was negatively correlated with the quality of life ( b = -5.559, t = -2.645, P = 0.009) . Pearson correlation analysis showed that acceptance of disease was positively correlated with quality of life ( r = 0.293, P<0.001) , and acceptance of disease was positively correlated with many dimensions of quality of life including intestinal function, systemic symptoms, emotional function and social function (all P<0.05) . Conclusions:Disease activity and disease acceptance can independently affect the quality of life of patients with IBD. The higher the disease acceptance, the lower the disease activity, and the higher the quality of life of patients.
