A report of two cases of hypoadrenocorticism caused by megestrol acetate
10.3760/cma.j.cn311282-20240919-00427
- VernacularTitle:醋酸甲地孕酮致肾上腺皮质功能减退二例病例报道
- Author:
Ruoyu ZHOU
1
;
Yuanyuan LIU
;
Meijuan DONG
;
Yanlong BU
;
Zhaohui CUI
Author Information
1. 南京医科大学附属淮安第一医院内分泌科，淮安 223300
- Publication Type:Journal Article
- Keywords:
Megestrol acetate;
Hypoadrenocorticism;
Adrenocorticotropic hormone;
Cortisol
- From:
Chinese Journal of Endocrinology and Metabolism
2025;41(3):242-244
- CountryChina
- Language:Chinese
-
Abstract:
Megestrol acetate is widely used in clinical practice and offers benefits to patients. However, it carries potential adverse effects, such as hypoadrenocorticism, which is often overlooked due to its atypical clinical manifestations. This report describes two cases of megestrol acetate-induced hypoadrenocorticism. Through a review of relevant literature, the mechanisms, clinical characteristics, and treatment strategies are summarized to enhance clinicians′ awareness of this potential complication.
