Focusing on the status, challenges and countermeasures of mpox susceptibility in children

VernacularTitle:关注儿童猴痘易感性的现状、挑战与应对
Author: Qinghua LU ¹ ; Dingle YU ; Xiang MA ; Jun YIN ; Lin MA ; Yonghong YANG
Author Information

1. 深圳市儿童医院呼吸科，深圳　518038
Publication Type:Journal Article
Keywords: Monkeypox; Child; Signs and symptoms; Therapy; Communicable disease control
From: Chinese Journal of Dermatology 2025;58(10):910-913
CountryChina
Language:Chinese
Abstract: Since the global outbreak in 2022, the mpox epidemic has evolved from an African endemic to a public health emergency of international concern. The 2024 mpox outbreak in the Democratic Republic of the Congo caused by the Clade Ⅰb lineage is yet another wake-up call, with markedly higher prevalence and fatality rates observed among children under 15 years of age, thereby presenting new challenges for the children. Therefore, it is necessary to strengthen prevention and control, block mother-to-child transmission routes, and establish innovative models with active community participation to reduce the risk of mpox transmission. In the future, it is urgent to analyze molecular mechanisms underlying the mother-to-child transmission of the virus, develop targeted antiviral drugs, establish a pediatric critical disease scoring system, and incorporate mpox vaccines into the World Health Organization′s expanded programme on immunization.