Application advance of cytokine-derived biological agents in inflammatory bowel disease
10.3760/cma.j.cn101480-20201104-00123
- VernacularTitle:细胞因子衍生的生物制剂在炎症性肠病中的应用进展
- Author:
Fangmei LING
1
;
Junrong LI
1
;
Yidong CHEN
1
;
Mingyang XU
1
;
Liangru ZHU
1
Author Information
1. 华中科技大学同济医学院附协和医院消化内科，武汉 430022
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Cytokine;
Biological agents;
Targeted therapy;
Interleukin;
Tumor necrosis factor;
Transforming growth factor;
Interferon
- From:
Chinese Journal of Inflammatory Bowel Diseases
2021;05(4):342-346
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of inflammatory bowel disease (IBD) , especially mucosal immunity, has made rapid progress, and the emergence of cytokine targets has greatly promoted the treatment of IBD. According to the different effects, biological agents targeting cytokines can be divided into anti-inflammatory cytokine-derived biological agents and pro-inflammatory cytokine-derived biological agents, which are currently in different stages of research. This article reviews the application and prospect of cytokine-derived biological agents in maintaining intestinal immune balance, and provides some reference for clinical treatment of IBD.
