T2 mapping for quantitatively evaluating changes of junctional zone and outer myometrium caused by endometrial fibrosis
10.13929/j.issn.1003-3289.2025.07.018
- VernacularTitle:T2 mapping定量评估子宫内膜纤维化所致结合带及外肌层变化
- Author:
Yucan CHEN
1
;
Huanhuan LIANG
;
Nan ZHOU
;
Hui ZHU
;
Peipei JIANG
;
Qing HU
;
Yongjing FENG
;
Yali HU
;
Zhengyang ZHOU
Author Information
1. 南京大学医学院附属鼓楼医院医学影像科,江苏南京 210008
- Publication Type:Journal Article
- Keywords:
endometrium;
fibrosis;
infertility,female;
magnetic resonance imaging;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2025;41(7):1121-1124
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of T2 mapping for quantitatively evaluating the changes of junctional zone and outer myometrium caused by endometrial fibrosis.Methods A total of 73 infertility patients with endometrial fibrosis confirmed by hysteroscopy(disease group)and 33 healthy women of childbearing age(control group)were prospectively enrolled,and MR examinations were performed at the late proliferative phase of endometrium.The thickness and T2 value of junctional zone,T2 value of outer myometrium on anterior,posterior and fundus wall of midsagittal corpus uteri were measured,and the mean value of the above measurements on the three walls were calculated.Receiver operating characteristic curves were constructed,the areas under the curves(AUC)were calculated to explore the efficacy of those with significant difference among the mean thickness and the mean T2 value of junctional zone,the mean T2 value of outer myometrium and their combination for evaluating endometrial fibrosis.Results The thickness and T2 value of anterior wall,posterior wall,fundus wall and the mean junctional zone in disease group were all significantly higher than those in control group(all P＜0.001).No significant difference of T2 value of anterior wall,posterior wall,fundus wall nor the mean outer myometrium was found between groups(all P＞0.05).The mean thickness and the mean T2 value of junctional zone and their combination could be used to effectively evaluate endometrial fibrosis,with AUC of 0.839,0.822 and 0.922,respectively,and their combination had the best performance(both P＜0.01).Conclusion T2 mapping could be used to quantitatively evaluate the injury of junctional zone caused by endometrial fibrosis.
