Preoperative magnetization transfer imaging for predicting pancreatic fistula after distal pancreatectomy
10.13929/j.issn.1003-3289.2025.07.017
- VernacularTitle:术前磁化转移成像预测远端胰腺术后胰瘘
- Author:
Mingming YANG
1
;
Ya LAN
;
Derui HU
;
Junxin LYU
;
Xinyue ZHANG
;
Jinggang ZHANG
;
Jie CHEN
;
Wei XING
Author Information
1. 苏州大学附属第三医院放射科,江苏常州 213003
- Publication Type:Journal Article
- Keywords:
pancreatectomy;
pancreatic fistula;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2025;41(7):1117-1120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of preoperative magnetization transfer imaging(MTI)for predicting postoperative pancreatic fistula(POPF)after distal pancreatectomy(DP).Methods A total of 65 patients with pancreatic tumor who underwent DP and preoperative MR scanning were retrospectively enrolled and divided into clinically relevant POPF(CR-POPF)group(n=14,with grade B or C fistula),biochemical fistula group(n=31,postoperative drain fluid amylase level exceeding 3 times the upper limit of normal)and non-fistula group(n=20,postoperative drain fluid amylase level not exceeding 3 times the upper limit of normal)based on postoperative records.Clinical data and magnetization transfer ratio(MTR)of pancreatic tissue at the surgical margin were compared among 3 groups.The predictive value of MTR for CR-POPF was evaluated according to the area under the curve(AUC)of receiver operating characteristic(ROC)curve.Results Patients' age,intraoperative blood loss and the proportion of pancreatic ductal adenocarcinoma in both CR-POPF group and biochemical fistula group were lower than those in non-fistula group(all adjusted P＜0.05),while no significant difference was found between the former two groups(all adjusted P＞0.05).MTR of pancreatic tissue at the surgical margin in CR-POPF group was lower than that in both biochemical fistula group and non-fistula group(both P＜0.05),whereas no statistical difference was detected between the latter two groups(P＞0.05).The AUC of MTR for predicting CR-POPF after DP was 0.727.Conclusion Preoperative MTI could be used to predict POPF after DP.
