Changes of brain functional connectivity in clinical frontline physicians under high occupational stress risk

VernacularTitle:高度职业紧张风险下临床一线医师脑功能连接改变
Author: Yanwei ZHANG ¹ ; Han WANG ; Zexuan WANG ; Cunzhao NIU ; Yan ZHANG ; Ge ZHANG
Author Information

1. 中国人民解放军联勤保障部队第九八〇医院放射诊断科,河北石家庄 050000
Publication Type:Journal Article
Keywords: medical staff; brain; occupational stress; magnetic resonance imaging; functional connectivity; prospective studies
From: Chinese Journal of Medical Imaging Technology 2025;41(7):1037-1041
CountryChina
Language:Chinese
Abstract: Objective To observe changes of brain functional connectivity in clinical frontline physicians under high occupational stress risk using gradient analysis based on MRI.Methods Totally 25 clinical frontline physicians were prospectively enrolled as observation group,while 25 non-medical staff in hospital taken as controls(control group).Brain resting-state functional MRI were acquired and preprocessed with Brainspace toolbox.Brain functional connectivity gradients were calculated,and the gradient components were compared between groups.Results In hierarchical structures of gradient components 1 and 2,significant increase of gradient components were noticed in observation group,mainly including default mode network,visual network and dorsal attention network related brain regions.Conclusion Gradient components of single modal brain regions in clinical frontline physicians significantly increased under high occupational stress risk.