Imaging guided percutaneous microwave ablation for unresectable pancreatic cancer:A multicenter retrospective study
10.13929/j.issn.1003-3289.2025.07.015
- VernacularTitle:影像学引导下经皮微波消融治疗不可切除胰腺癌:多中心回顾性分析
- Author:
Shuilian TAN
1
;
Jie ZHOU
;
Ping LIANG
;
Xiaoling YU
;
Xin YE
;
Gang DONG
;
Xiang JING
;
Guanghui HUANG
;
Zhen WANG
;
Mengfan PENG
;
Yan ZHOU
;
Jie YU
;
Zhiyu HAN
;
Fangyi LIU
;
Hongjian GAO
;
Yubo ZHANG
;
Zhigang CHENG
Author Information
1. 中国人民解放军总医院第五医学中心介入超声科,北京 100853
- Publication Type:Journal Article
- Keywords:
pancreatic neoplasms;
ablation techniques;
ultrasonography;
tomography,X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2025;41(7):1109-1112
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility and safety of ultrasound-guided percutaneous microwave ablation for unresectable pancreatic cancer.Methods Totally 84 patients who underwent ultrasound-guided percutaneous microwave ablation for unresectable pancreatic cancer were enrolled,and the technical success rate,complete ablation rate,complication rate,pain relief rate and survival time,etc.were observed.Results The median age of 84 cases was 61.5 years.Totally 86 tumors,including 44.19%(38/86)at the head/neck and 55.81%(48/86)at the body/tail of pancreas were detected,and a total of 85 ablation sessions were performed with the median ablation energy applied per tumor of 9.90(1.08,21.60)kJ and the complete ablation rate of 42.86%(36/84).The technical success rate was 100%(85/85).Thirty-nine complication events occurred in 25 cases,no ablation-related death.Among 34 patients underwent ablation mainly for pain symptoms,the pain score decreased from(6.22±1.12)points before treatment to(1.94±1.64)points after treatment(P<0.001).During 6.8(3.3,12.9)months' follow-up,the mean survival time was(8.5±6.7)months,and all 47 patients died due to tumor progression.Conclusion Ultrasound-guided percutaneous microwave ablation was safe and feasible for unresectable pancreatic cancer.