Research progress of the influence of appendectomy on ulcerative colitis

VernacularTitle:阑尾切除对溃疡性结肠炎影响的研究进展
Author: Zongjin ZHANG ¹ ; Ping LAN ; Xianrui WU
Author Information

1. 中山大学附属第六医院结直肠外科，广州　510655
Publication Type:Journal Article
Keywords: Appendectomy; Ulcerative colitis; Incidence; Colorectal neoplasms; Disease course
From: Chinese Journal of Inflammatory Bowel Diseases 2021;05(1):50-54
CountryChina
Language:Chinese
Abstract: Ulcerative colitis (UC) is a chronic nonspecific inflammatory bowel disease that is considered to be multifactorial with environmental factors, genetic basis, intestinal immune regulation and intestinal flora. The appendix may effect intestinal immune system regulation and microecological stability. Previous studies indicated appendectomy may reduce the risk of UC incidence and alleviate the severity of the disease. And appendectomy for relapsed and refractory UC may have a certain therapeutic effect. However, appendectomy as a treatment for UC is still controversial. This article discusses the impact of appendectomy on UC in the view of disease incidence, disease course, and basic research.