Clinical analysis of 26 cases with solitary rectal ulcer syndrome
10.3760/cma.j.cn101480-20200902-00099
- VernacularTitle:26例孤立性直肠溃疡综合征临床分析
- Author:
Junrong LI
1
;
Fangmei LING
;
Yidong CHEN
;
Liduan ZHENG
;
Liangru ZHU
Author Information
1. 华中科技大学同济医学院附属协和医院消化内科，武汉 430022
- Publication Type:Journal Article
- Keywords:
Solitary rectal ulcer syndrome;
Rectal prolapse;
Endoscope;
Pathology
- From:
Chinese Journal of Inflammatory Bowel Diseases
2021;05(1):68-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical characteristics of solitary rectal ulcer syndrome (SRUS) .Methods:Retrospective analysis was performed on the data of 26 patients with SRUS diagnosed by pathology and admitted to Union Hospital, Tongji Medical College, Huazhong University of Science and Technology from June 2015 to November 2019. A descriptive method was used to collect the general information, clinical manifestations, endoscopy, pathological examination, treatment and prognosis of patients.Results:A total of 26 patients were enrolled, including 11 males and 15 females, with average age of (41.96±13.83) years old and median duration of 21 (0.2-480) months from onset to diagnosis. The main clinical manifestations were rectal bleeding in 15 (57.69%) cases, rectal prolapse in 9 (34.62%) , perianal pain in 6 (23.08%) , body mass loss in 6 (23.08%) and rectal mucus in 5 (19.23%) . Seventeen patients underwent endoscopic examination, endoscopic features included ulcer in 6 (35.29%) cases, rectal polyp in 5 (29.41%) , protuberance in 4 (23.53%) , hyperplasia and swelling in 4 (23.53%) , erosion in 3 (17.65%) , either alone or in combination. Histological examination of rectal biopsies revealed that the characteristic features were mucosal surface erosion and ulcer in 11 (42.31%) cases, lamina propria fibrosis in 8 (30.77%) , mucosal gland deletion or decreased secretion in 6 (23.08%) , inflammatory cell infiltration in 5 (19.23%) , vascular changes in 5 (19.23%) , and crypts alteration in 4 (15.38%) . Five patients (19.23%) received medical treatment and 21 patients (80.77%) received surgery. Symptoms except rectal prolapse disappeared or were improved in all the patients after treatment.Conclusion:The clinical and endoscopic features of SRUS are variable. Pathology is crucial for diagnosis and differential diagnosis. Both the medical and surgical treatment are effective for SRUS.
