Pediatric tumor predisposition syndrome:Management strategy and whole-body MRI screening

VernacularTitle:儿童肿瘤易感综合征:管理策略及全身MRI筛查
Author: Xin LI ¹ ; Jianbo SHAO
Author Information

1. 天津市第二人民医院放射科,天津 300192
Publication Type:Journal Article
Keywords: child; tumor predisposition syndrome; magnetic resonance imaging
From: Chinese Journal of Medical Imaging Technology 2025;41(8):1280-1283
CountryChina
Language:Chinese
Abstract: Pediatric tumor predisposition syndrome(TPS)is a heterogeneous group of diseases caused by inherited gene mutations or germline mutations,which increasing risk of tumors.Screening pediatric TPS remains a multidisciplinary,multimodal and longitudinal management process.Imaging techniques are beneficial for early detection of tumors reducing mortality rates.Whole-body MRI,combined with multidisciplinary follow-up,including pediatric oncology,pediatric surgery,endocrinology,radiology,hematology and genetics,is helpful to management of pediatric TPS.The research progresses in management strategy and whole-body MRI screening of pediatric TPS were reviewed in this article.