Diagnosis and treatment strategies of inflammatory bowel disease complicated with rheumatic immune diseases
10.3760/cma.j.cn101480-20201027-00116
- VernacularTitle:炎症性肠病合并风湿免疫病诊治策略
- Author:
Xiaoman ZU
1
;
Shu XU
1
;
Lihui LIN
1
;
Rui FENG
1
;
Baili CHEN
1
;
Minhu CHEN
1
;
Yao HE
1
Author Information
1. 中山大学附属第一医院消化内科，广州 510080
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Rheumatic immune disease;
Spinal arthritis;
Rheumatoid arthritis;
Systemic lupus erythematosus;
Diagnosis;
Treatment
- From:
Chinese Journal of Inflammatory Bowel Diseases
2021;05(1):21-26
- CountryChina
- Language:Chinese
-
Abstract:
Both inflammatory bowel disease (IBD) and rheumatic immune diseases have abnormal immune response. Genome-wide association studies have found that there is genetic overlap between IBD and certain rheumatic immune diseases, suggesting that there may be a common pathogenesis. The risk of rheumatic immune disease in IBD patients is higher than that of normal population, which brings challenges for diagnosis and treatment. When IBD patients are complicated with rheumatic immune diseases including spinal arthritis, rheumatoid arthritis, systemic lupus erythematosus, Sj?gren′s syndrome, vasculitis and systemic sclerosis, the diagnosis should be comprehensive and the treatment should be specific. Drugs that can cover the two diseases should be selected as far as possible, or individualized treatment should be carried out according to the severity and activity of the two diseases.It is suggested to avoid drugs that treat one disease but increase the risk of another. Therefore, gastroenterologists should cooperate with rheumatologists, and adopt multidisciplinary diagnosis and treatment mode to formulate the best treatment plan for patients. This paper summarizes the diagnosis and treatment strategies of IBD complicated with common rheumatic immune diseases, in order to provide references for clinical work.
