Correlation between serum uric acid and adverse prognosis in elderly patients with heart failure
10.3969/j.issn.1009-0126.2024.12.007
- VernacularTitle:老年心力衰竭患者血清尿酸水平与不良预后的相关性分析
- Author:
Wenyou WANG
1
;
Ping ZHOU
;
Juanjuan ZHENG
;
Ci LÜ
;
Chenchen ZHANG
;
Tong WANG
;
Wei WANG
;
Lingyan LIU
Author Information
1. 400038 重庆,陆军军医大学第一附属医院老年医学与特勤医学科
- Publication Type:Journal Article
- Keywords:
heart failure;
uric acid;
prognosis;
correlation of data
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(12):1414-1418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of SUA level on adverse prognosis in elderly pa-tients with HF.Methods A retrospective analysis was conducted on 1583 patients admitted to Zigong Fourth People's Hospital between December 2016 and June 2019 due to a diagnosis of HF.The patients were divided into low SUA group(≤386.8 μmol/L,523 cases),medium SUA group(386.9-523.6 μmol/L,537 cases),and high SUA group(＞523.6 μmol/L,523 cases).Multivari-ate logistic regression model was employed to assess the relationship between SUA level and ad-verse outcomes in the elderly HF patients.Results The incidence of adverse events was signifi-cantly higher in the high SUA group than that in the low SUA group in 6 months of follow-up(P＜0.05).When compared with the low SUA group,the high SUA group had a significantly in-creased risk of readmission within 6 months(RR=1.531,95％CI:1.180-1.988,P=0.001),and elevated risk of compound events(RR=1.624,95％CI:1.255-2.102,P=0.000).NYHA grade Ⅳand diabetes were independent influencing factors for 6-month adverse prognosis in elderly pa-tients HF(P＜0.05,P＜0.01).An approximately linear trend was observed in the dose-response relationship of SUA level and adverse prognosis,indicating an increased risk of short-term death,readmission,and compound events as increment of SUA level.Conclusion Higher SUA level is significantly associated with adverse prognosis in elderly HF patients.
