Analysis on correlation between severity of ulcerative colitis patients under endoscopy and laboratory examination indexes

Xiao LI; Xin LIU; Haitao SHI; Yuan FENG; Gang ZHAO; Fenrong CHEN; Jiong JIANG; Danyan CHANG; Juhui ZHAO; Shiyang MA

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Analysis on correlation between severity of ulcerative colitis patients under endoscopy and laboratory examination indexes

VernacularTitle:溃疡性结肠炎患者内镜严重程度与实验室检查指标相关性分析
Author: Xiao LI ¹ ; Xin LIU ¹ ; Haitao SHI ¹ ; Yuan FENG ¹ ; Gang ZHAO ¹ ; Fenrong CHEN ¹ ; Jiong JIANG ¹ ; Danyan CHANG ¹ ; Juhui ZHAO ¹ ; Shiyang MA ¹
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1. 西安交通大学第二附属医院消化内科，西安　710004
Publication Type:Journal Article
Keywords: Ulcerative colitis; Mayo colonoscopy score; Platelet; Cholesterol; Serum uric acid
From: Chinese Journal of Inflammatory Bowel Diseases 2020;04(2):119-123
CountryChina
Language:Chinese
Abstract: Objective:To examine the correlation of the severity of ulcerative colitis (UC) under endoscopy with blood routine, coagulation, lipid, uric acid and other laboratory indexes.Methods:Clinical data of 90 UC patients in The Second Affiliated Hospital of Xi′an Jiaotong University from January to December 2018 were retrospectively collected. The patients were divided into three groups as light, medium and heavy according to Mayo colonoscopy score. The laboratory indexes were compared among 3 groups and the correlations between Mayo colonoscopy score and laboratory indexes were analyzed.Results:Among light, medium, and heavy groups, differences of the platelet count [ (205.00 ± 61.18) × 10 9/L vs. (240.33 ± 82.90) × 10 9/L vs. (285.55 ± 107.60) × 10 9/L, P=0.020], hemoglobin [ (129.70 ± 16.22) g/L vs. (135.35 ± 20.40) g/L vs. (121.33 ± 27.82) g/L, P=0.034], low-density lipoprotein (LDL) [ (2.44 ± 0.50) mmol/L vs. (2.54 ± 0.67) mmol/L vs. (2.10 ± 0.62) mmol/L, P=0.010], cholesterol [ (4.07 ± 0.60) mmol/L vs. (4.02 ± 0.94) mmol/L vs. (3.50 ± 0.80) mmol/L, P=0.017], fibrinogen [ (2656.00 ± 371.54) mg/L vs. (3034.50 ± 826.52) mg/L vs. (3390.26 ± 1013.61) mg/L, P=0.039] were statistically significant (all P<0.05) . Mayo colonoscopy score was negatively correlated with LDL and cholesterol (all P<0.05) , while it was positively correlated with platelet count and fibrinogen (all P<0.05) . Conclusion:Testing the relevant laboratory indexes of UC patients can help evaluate the intestinal condition.