Role of triggering receptor expressed on myeloid cells -1 in inflammatory bowel disease
- VernacularTitle:髓样细胞触发受体-1在炎症性肠病中的研究进展
- Author:
Li GENG
1
;
Muhan ZHANG
1
;
Xuping WANG
1
;
Dandan WANG
1
;
Beibei YANG
1
;
Chuang GAO
1
;
Xiaobo DU
1
;
Baisui FENG
1
Author Information
- Publication Type:Journal Article
- Keywords: Inflammatory bowel disease; Triggering receptor expressed on myeloid cells -1; Toll-like receptor; Soluble triggering receptor expressed on myeloid cells
- From: Chinese Journal of Inflammatory Bowel Diseases 2020;04(2):154-157
- CountryChina
- Language:Chinese
- Abstract: Inflammatory bowel disease (IBD) is a group of recurrent chronic intestinal inflammatory diseases. The precise etiology of IBD remains unclear, but the inappropriate immune response is considered the leading cause of IBD. More and more studies indicated that triggering receptor expressed on myeloid cells (TREM) -1 have regulated multiple signaling pathways. This review will focus specifically on recent insights into the role of TREM-1 proteins in IBD development, and discuss opportunities for novel treatment approaches.
