Clinical effects of Shenzhu Jianpi Zengshi Decoction on patients with infantile anorexia
10.3969/j.issn.1001-1528.2024.10.017
- VernacularTitle:参术健脾增食汤对小儿厌食症患者的临床疗效
- Author:
Xiao-yan LIU
1
;
Yao CUI
;
Hai-yan WANG
;
Li ZHAO
;
Xiao RONG
;
Ying-fang CHEN
Author Information
1. 河北省中医院儿科,河北石家庄050011;河北省中西医结合胃肠病研究重点实验室,河北石家庄050011;河北省脾肾病证中医治疗技术创新中心,河北 石家庄 050011
- Publication Type:Journal Article
- Keywords:
Shenzhu Jianpi Zengshi Decoction;
Compound Pepsin Granules;
infantile anorexia
- From:
Chinese Traditional Patent Medicine
2024;46(10):3293-3297
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the clinical effects of Shenzhu Jianpi Zengshi Decoction on infantile anorexia.METHODS One hundred and seventy-six patients were randomly assigned into control group (88 cases) for 21-day administration of Compound Pepsin Granules,and observation group (88 cases) for 21-day administration of both Shenshu Jianpi Zengshi Decoction and Compound Pepsin Granules.The changes in clinical effects,TCM syndrome scores,infantile growth and nutritional status indices ( height,body weight,BMI,food intake,hemoglobin,CD4+,CD8+),appetite regulators ( leptin,vasoactive peptide,motilin,gastrin,human growth hormone releasing peptide),incidence of adverse reactions and recurrence rate were detected.RESULTS The observation group demonstrated higher total effective rate than the control group ( P<0.05 ),along with lower recurrence rate ( P<0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,CD8+( P<0.05),and increased height,body weight,BMI,food intake,hemoglobin,CD4+,appetite regulators ( P<0.05),especially for the observation group ( P<0.05).No significant difference in incidence of adverse reactions was found between the two groups (P>0.05).CONCLUSION For the patients with infantile anorexia,Shenzhu Jianpi Zengshi Decoction can safely and effectively alleviate clinical symptoms,improve appetite and nutritional status,and reduce recurrence rate.
