Research Progress in the Mechanism of Acupuncture and Moxibustion for the Treatment of Ulcerative Colitis
10.19879/j.cnki.1005-5304.202312437
- VernacularTitle:针灸治疗溃疡性结肠炎机制研究进展
- Author:
Xuan YIN
1
;
Shifen XU
1
;
Xiutian GUO
1
Author Information
1. 上海中医药大学附属市中医医院,上海 200071
- Publication Type:Journal Article
- Keywords:
acupuncture and moxibustion;
ulcerative colitis;
mechanism study;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(1):186-191
- CountryChina
- Language:Chinese
-
Abstract:
The development of ulcerative colitis(UC)is closely related to genetic and environmental factors,impaired intestinal mucosal barrier function,intestinal immunological disorders and dysbiosis of intestinal bacterial flora.Acupuncture and moxibustion treatment has been emphasized for improving intestinal inflammation in UC.In this article,the mechanism of acupuncture and moxibustion in alleviating UC was reviewed from the aspects of immune cells,inflammatory factors and intestinal flora,and believed that acupuncture may exert therapeutic effects by improving the immune homeostasis among T-lymphocytes,inhibiting the expression of pro-inflammatory factors including IL-1β,IL-6 and IL-8,regulating the abundance of different species of intestinal flora,modulating macrophage polarization,and inhibiting oxidative stress.The possible mechanism of acupuncture and moxibustion in the treatment of UC was summarized to provide reference for the related research of inflammatory bowel disease.
