Study on the TCM Syndrome Distribution Law of Patients with Henoch-Schonlein Purpura Nephritis in Shaanxi Area
10.19879/j.cnki.1005-5304.202406120
- VernacularTitle:陕西地区过敏性紫癜性肾炎患者中医证候分布规律研究
- Author:
Wenjun YANG
1
;
Sheng DONG
;
Ruolan ZHAO
;
Genping LEI
;
Ting WANG
Author Information
1. 陕西中医药大学,陕西咸阳 712046
- Publication Type:Journal Article
- Keywords:
Henoch-Schonlein purpura nephritis;
TCM syndromes;
clustering analysis;
principal component analysis;
complex network analysis
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(1):146-150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the syndrome characteristics of Henoch-Schonlein purpura nephritis in Shaanxi area;To provide reference for TCM clinical syndrome differentiation and treatment.Methods Clinical data on patients diagnosed with Henoch-Schonlein purpura nephritis who received outpatient or inpatient treatment at five hospitals in Shanxi area including Hospital of Shaanxi University of Chinese Medicine and Yulin Traditional Chinese Medicine Hospital etc from August 2020 to August 2022 were under retrospective collection.TCM syndrome distribution law in patients with Henoch-Schonlein purpura nephritis in Shaanxi area was concluded through frequency statistics,clustering analysis,principal component analysis,and complex network analysis.Results Totally 143 patients were included,involving 64 symptoms.3 groups of syndromes were obtained after clustering analysis,and principal component analysis was performed for each group of syndromes.Using complex network analysis and combining the results of clustering analysis and principal component analysis,classification groups for each group of main symptoms and comorbidities were formed,and their main syndrome classification was determined:qi-yin deficiency syndrome,accounting for 47.55％;spleen deficiency and dampness,accounting for 34.97％;wind-heat attacking the exterior,accounting for 17.48％.Conclusion The syndromes of Henoch-Schonlein purpura nephritis in Shaanxi area are mainly divided into three types:qi-yin deficiency,spleen deficiency and dampness and wind-heat attacking the exterior.Among them,qi-yin deficiency is the most common.
