Impact of opioid-free anesthesia on the recovery of patients during the awakening phase after transurethral resection of the prostate
10.3969/j.issn.1673-9701.2024.35.014
- VernacularTitle:无阿片类药物麻醉对前列腺电切术患者苏醒期恢复情况的影响
- Author:
Changxiong XU
1
;
Jiahui TU
1
;
Tao LIU
1
Author Information
1. 湖州市第一人民医院麻醉科,浙江湖州 313000
- Publication Type:Journal Article
- Keywords:
Opioid-free anesthesia;
Resection of prostate;
Emergence agitation
- From:
China Modern Doctor
2024;62(35):64-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate how opioid-free anesthesia affects the occurrence of emergence agitation(EA)during recovery after transurethral resection of prostate(TURP).Methods A total of 78 patients undergoing TURP from May 2023 to June 2024 in the First People's Hospital of Huzhou were selected as the study subjects.Patients were assigned to two groups using a random number table method,group F received fentanyl(3μg/kg)+propofol(2mg/kg),and group LY received esketamine(0.3mg/kg)+propofol(2mg/kg),39 cases in each group.EA was assessed every 5 minutes following the removal of the laryngeal mask,and pain levels were measured using the visual analog score(VAS).Mean arterial pressure(MAP)and heart rate(HR)were recorded at admission(T0),immediately after laryngeal mask insertion(T1),3 minutes after(T2),6 minutes after(T3),and 9 minutes after(T4).Data on rescue analgesia,operation time,recovery time,and adverse reactions during recovery,such as agitation,nausea,vomiting,hypoxemia,nightmares,and hallucinations were also recorded.Results Compared to group F,incidence of postoperative EA,highest VAS score,and extubation time in group LY were lower(P＜0.05).The highest sedation score in group LY was greater than that in group F(P＜0.05).The comparison of HR and MAP at each time point between two groups showed statistically significant differences from T1 to T4(P＜0.05).Conclusion The opioid-free anesthesia regimen reduces incidence of EA and postoperative pain scores in TURP patients without increasing adverse reactions during recovery.
