Attributable disease burden of active smoking on cancer mortality among residents aged 30 and above in Zhejiang Province
10.3760/cma.j.cn112338-20241209-00783
- VernacularTitle:浙江省30岁及以上居民主动吸烟对癌症死亡的归因疾病负担分析
- Author:
Yue XU
1
;
Xiujing HU
;
Xiaoyan ZHOU
;
Heni CHEN
;
Xuehai ZHANG
;
Na LI
;
Min YU
Author Information
1. 浙江省疾病预防控制中心健康教育所，杭州 310051
- Publication Type:Journal Article
- Keywords:
Smoking;
Cancer;
Population attributable fraction;
Years of life lost
- From:
Chinese Journal of Epidemiology
2025;46(8):1360-1365
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the attributable burden of active smoking on the deaths of cancer in inhabitants aged 30 years and above in Zhejiang Province.Methods:Comparative risk assessment approach in the Global Burden of Disease Study was used with the data from Zhejiang Adult Tobacco Surveillance System and Death Monitoring Surveillance System in 2020, and population attributable fraction (PAF), years of life lost (YLL), work of potential years of life lost (WPYLL) attributed to smoking on the deaths of cancer in inhabitants aged 30 years and above in Zhejiang Province were calculated with a linear regression model.Results:In 2020, there were 81 536 cancer deaths aged 30 years and above in the surveillance areas of Zhejiang Province, of which 24 518 were attributed to active smoking (PAF: 30.07%, attributable mortality rate: 55.04/100 000). The YLL was 553 078 person-years, with a standardized YLL rate of 12.40‰, and the WPYLL was 56 606 person-years. Among various cancer types, laryngeal cancer had the highest smoking-attributable PAF (44.75%), while lung cancer accounted for the most significant number of attributable deaths and life loss, with an age-standardized YLL rate of 4.65‰.Conclusions:Active smoking is a significant risk factor for cancer mortality in Zhejiang Province, with lung cancer posing the most significant disease burden. It is urgent to advance tobacco control legislation, strengthen targeted interventions, and promote early cancer screening to reduce the disease burden associated with smoking-related cancers effectively.
