Interpretation of the British Society for Rheumatology 2024 guidelines on managing Sj?gren′s syndrome in adults and adolescents
10.3760/cma.j.cn141217-20250209-00037
- VernacularTitle:《2024英国风湿病学会指南：成人和青少年起病的干燥综合征管理》解读
- Author:
Wenjing YANG
1
;
Hong LAN
1
;
Yingqian MO
1
Author Information
1. 中山大学孙逸仙纪念医院风湿免疫科，广州 510120
- Publication Type:Journal Article
- Keywords:
Sj?gren′s syndrome;
Guidebook;
Interpretation
- From:
Chinese Journal of Rheumatology
2025;29(7):561-567
- CountryChina
- Language:Chinese
-
Abstract:
Sj?gren′s syndrome (SS) is a prevalent systemic autoimmune disorder characterized by significant heterogeneity and complexity, which present considerable challenges in diagnosis and management. In 2017, the British Society for Rheumatology (BSR) released guidelines for the management of adult SS. Based on this, the BSR identified 19 key issues and subsequently formulated 47 evidence-based recommendations in 2024,including 11 recommendations supported by level A evidence. Compared to the previous guidelines, the 2024 version has expanded its scope to include novel recommendations in diagnostic approaches (such as salivary gland ultrasonography and labial salivary gland biopsy)and in the management of specific patient populations (such as patients with juvenile-onset and pregnant patients). There are also substantial updates regarding the local treatment of keratoconjunctivitis sicca. However, the use of systemic medications still requires additional robust evidence from clinical studies. This article aims to critically discuss these updates to provide rheumatologists with valuable insights for clinical decision-making and to offer guidance for patients with SS in their self-management strategies.
