Progress of non-invasive screening of early-onset colorectal cancer
10.3760/cma.j.cn115355-20240624-00307
- VernacularTitle:早发性结直肠癌的无创筛查研究进展
- Author:
Xinxuan ZHAO
1
;
Haiyi LIU
Author Information
1. 山西医科大学第二临床医学院，太原 030013
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Screening;
Non-invasive diagnosis;
Fecal immunochemical test
- From:
Cancer Research and Clinic
2025;37(10):793-797
- CountryChina
- Language:Chinese
-
Abstract:
The rapid increase in the incidence of early-onset colorectal cancer (EOCRC) has significantly reduced the median age of diagnosis for this disease, resulting in a substantial socio-economic burden. Currently, colonoscopy remains the primary screening tool for colorectal cancer; however, compliance among the target population is low, partly due to the invasive nature of the procedure. Screening plays a crucial role in disease prevention and treatment, as it can effectively increase disease detection rates and significantly improve the prognosis of patients through early intervention. Therefore, the development of highly sensitive and specific early screening methods for EOCRC is of considerable clinical importance. This article reviews the current screening strategies for early diagnosis of EOCRC patients, with a focus on the research progress of non-invasive screening such as fecal and blood-based testing, aiming to provide references for clinicians in selecting screening methods.
