Progress of Krüppel-like factor 5 in tumors
10.3760/cma.j.cn115355-20240805-00381
- VernacularTitle:Krüppel样因子5在肿瘤中的研究进展
- Author:
Yubin YANG
1
;
Tao ZHANG
;
Ruoqi WANG
;
Juanjuan GUO
;
Xiaoming HOU
Author Information
1. 甘肃中医药大学，兰州 730000
- Publication Type:Journal Article
- Keywords:
Krüppel-like factor 5;
Neoplasms;
Transcription factors
- From:
Cancer Research and Clinic
2025;37(9):713-716
- CountryChina
- Language:Chinese
-
Abstract:
Krüppel-like factor 5 (KLF5) has been confirmed as a key transcription factor in the occurrence and development of tumors, which is closely related to the malignant biological behaviors such as the proliferation and migration of tumor cells. This article summarizes the latest progress of KLF5 in tumor research, explores the mechanism and role of KLF5 in promoting tumor progression, aiming to further explore the potential of KLF5 as a therapeutic target and bring new thinking to the research in this field.
