Impact of preoperative oral carbohydrate on patients with cancer in perioperative period
10.12354/j.issn.1000-8179.2024.20241212
- VernacularTitle:术前口服碳水化合物对围术期肿瘤患者的影响
- Author:
Han JINYU
1
;
Zhang XIAOBEI
1
;
Wang ZHUN
1
;
Wang KAIYUAN
1
Author Information
1. 天津医科大学肿瘤医院麻醉科,国家肿瘤临床医学研究中心,天津市恶性肿瘤临床医学研究中心,天津市"肿瘤防治"重点实验室,天津市300060
- Publication Type:Journal Article
- Keywords:
preoperative oral carbohydrate (POC);
tumor;
perioperative period;
insulin resistance
- From:
Chinese Journal of Clinical Oncology
2024;51(20):1049-1053
- CountryChina
- Language:Chinese
-
Abstract:
Preoperative oral carbohydrates (POC) play an important role in modern anesthesia and surgery as part of enhanced recovery after surgery (ERAS). Oral carbohydrate intake before surgery can reduce preoperative anxiety,improve metabolic status,reduce postoper-ative insulin resistance,and reduce stress and inflammatory responses in patients,thereby reducing the occurrence of postoperative com-plications. Directed at a specific population of patients with tumors,an increasing number of studies are focusing on the effects of oral car-bohydrate intake before surgery on metabolism,immune function,postoperative complications,and even tumor recurrence. Notably,the direct effect of POC intake on the tumor itself remains unclear. Previous studies have suggested that a reasonable intake of carbohydrates may exhibit an inhibitory effect on tumor development through indirect mechanisms,such as regulating body metabolism and enhancing immune function. This review summarizes and analyzes the perioperative effects of preoperative carbohydrate load in patients with cancer and provides a theoretical basis for the preoperative preparation of these patients.