Increased level of myoglobin due to propofol
10.3760/cma.j.issn.1008-5734.2018.06.022
- VernacularTitle:丙泊酚致肌红蛋白升高
- Author:
Jing YANG
1
;
Yang DAI
;
Hua FAN
;
Huaguang WANG
;
Lihong LIU
Author Information
1. 100020,首都医科大学附属北京朝阳医院药事部
- Publication Type:Journal Article
- Keywords:
Anesthetics,intravenous;
Myoglobin;
Propofol
- From:
Adverse Drug Reactions Journal
2018;20(6):468-470
- CountryChina
- Language:Chinese
-
Abstract:
A 50-year-old female patient received mechanical ventilation via tracheal cannula and continuous venous pump of propofol 1.2 mg/(kg·h)for sedation in surgical intensive care unit (SICU) after liver transplantation. On day 4 after the operation,the ventilator and propofol were discontinued and laboratory test showed myoglobin (Mb)1 345 μg/L. On day 6 after the operation,the Mb level decreased to 803 μg/L. And on the same day,the mechanical ventilation via tracheal cannula and continuous venous pump of propofol 1. 538 mg/(kg·h ) for sedation was given again because of pleural effusion and atelectasis. After that,the patient′s Mb level keep increasing and,on day 10 after the operation,it increased to 1 465 μg/L. Propofol was stopped and the Mb level decreased to 638 μg/L 4 days later and then 320 μg/L 11 days later.
