Adverse reactions to Zhuangguguanjie Wan and cause analysis
10.3760/j.issn.1008-5734.2000.01.003
- VernacularTitle:壮骨关节丸不良反应原因分析
- Author:
Jinghua CHENG
1
;
Haodong CAI
1
Author Information
1. 北京地区药品不良反应监察中心,北京,100011
- Publication Type:Journal Article
- Keywords:
ZW;
adverse reactions;
liver damage
- From:
Adverse Drug Reactions Journal
2000;2(1):15-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To approach the clinical manifestations and pathogenesis of adverse reactions caused by Zhuangguguanjie Wan (ZW),a ready-prepared Chinese medicine,Methods:156 ZW-induced ADR cases in 1992 ～ 1998 were collected and reviewed from CBM,Beijing Centre for ADR Monitoring and Beijing Ditan Hospital.Results:ZW is generally for the aged and the most common manifestation is live damage characterized by cholestasis,which would be related with improper pattern identification,individual differences and toxicity of some ingredients in ZW.Conclusion:ZW administration needs liver function tested regularly because liver damage might be produced.It is suggested that ZW formula be readjusted.
