Abdominal type Henoch-Schonlein purpura caused by Polyethylene Glycol-Electrolyte Powder
10.3760/cma.j.issn.1008-5734.2018.01.011
- VernacularTitle:聚乙二醇电解质散诱发腹型过敏性紫癜
- Author:
Zhe WANG
1
;
Lina CHAI
;
Dongliang YANG
;
Yi QIAO
;
Aidong WEN
Author Information
1. 044000,山西省运城市中心医院药学部
- Publication Type:Journal Article
- Keywords:
Polyethylene glycols;
Drug therapy;
Purpura;
Schoenlein-Henoch
- From:
Adverse Drug Reactions Journal
2018;20(1):53-54
- CountryChina
- Language:Chinese
-
Abstract:
In order to identify the cause for abdominal pain and diarrhea by electronic colonoscopy, one male patient aged 54-year-old took orally polyethylene glycol-electrolyte powder including two bags of agents A and B respectively which were dissolved in 300 ml warm water,and taken 1 time every 20 minutes, for 4 times. Two hours later,many dark red spots with a diameter of 0.5 cm were scattered on both lower limbs which were partly fused into ecchymosis,with clear boundary and not faded after pressing. Meanwhile the patient developed abdominal paroxysmal colic and the pain site was not fixed. The stool,urine routine and kidney function were urgently examined,and their results were normal. The results of colonoscopy showed that the colonic mucosa was widely edematous and there were scattered spotty and patchy mucosal hyperemia,which were remarkable at descending colon and lower segment. It was considered to be abdominal type Henoch-Schonlein purpura which might be related with polyethylene glycol-electrolyte powder. After glucocorticoid and symptomatic treatment,the abdominal pain disappeared and ecchymosis subsided within 15 days.