Zoledronic acid injection induced conjunctivitis with blepharoptosis
10.3760/cma.j.issn.1008-5734.2018.01.021
- VernacularTitle:唑来膦酸注射液致结膜炎伴上睑下垂
- Author:
Chang CAO
1
;
Limin YOU
;
Jiangtao DU
;
Hexia GAN
;
Jiawei CAI
;
Tao SHI
Author Information
1. 361005,厦门大学附属成功医院药剂科
- Publication Type:Journal Article
- Keywords:
Conjunctivitis;
Blepharoptosis;
Zoledronic acid
- From:
Adverse Drug Reactions Journal
2018;20(1):71-73
- CountryChina
- Language:Chinese
-
Abstract:
A 67-year-old female patient with severe osteoporosis received an intravenous infusion of zoledronic acid injection 5 mg(100 ml). Twenty-four hours later,the patient developed conjunctival congestion in bilateral eyes,blurred vision,and difficult lifting of the right eyelid. Ofloxacin eye drops and polyethylene glycol eye drops were given,but the above symptoms were not improved markedly. On the 3rd day of zoledronate acid injection,conjunctivitis with blepharoptosis was diagnosed by an ophthalmologist. On the 4rd day,tobramycin dexamethasone eye drops and esculin and digitalisglycosides eye drops were given. Eight days later,the patient's eyes discomfort disappeared. It was considered that conjunctivitis with blepharoptosis was induced by zoledronic acid injection.
