New insights into the pathogenesis and clinical therapeutic strategies of melasma
- VernacularTitle:黄褐斑发病机制与临床对策的新认识
- Author:
Chengfeng ZHANG
1
;
Shanglin JIN
1
Author Information
- Publication Type:Journal Article
- Keywords: Melanosis; Skin aging; Gonadal hormones; Circadian rhythm; Melasma; Photoaging; Skin barrier
- From: Chinese Journal of Dermatology 2025;58(9):797-800
- CountryChina
- Language:Chinese
- Abstract: The etiology and pathogenesis of melasma have not been fully elucidated. This article summarizes the recent research progress on melasma, explores the roles of photoaging, skin barrier dysfunction, mast cell activation, sex hormone fluctuations, and circadian rhythm disturbances in its pathogenesis, with the aim of providing new directions for its clinical prevention and treatment. With a deeper understanding of the pathogenesis of melasma, future therapeutic strategies are expected to shift from solely addressing skin pigmentation to comprehensive approaches involving anti-photoaging therapies and skin repair interventions.
