Application of cell therapy in systemic lupus erythematosus
- VernacularTitle:细胞治疗在系统性红斑狼疮中的应用
- Author:
Mingyue LYU
1
;
Xiaoyong MAN
1
Author Information
- Publication Type:Journal Article
- Keywords: Lupus erythematosus, systemic; Cell therapy; Hematopoietic stem cell transplantation; Mesenchymal stem cells; Chimeric antigen receptor-T cells; Natural ki
- From: Chinese Journal of Dermatology 2025;58(4):374-377
- CountryChina
- Language:Chinese
- Abstract: Systemic lupus erythematosus is a chronic autoimmune disease that affects multiple organs and systems, and current treatment strategies can only result in clinical remission. In recent years, cell therapies have shown promising advancements in the treatment of autoimmune diseases, particularly chimeric antigen receptor technology has demonstrated potential as a transformative therapy for these diseases. This review summarizes the application and prospects of various cell therapies in systemic lupus erythematosus, including hematopoietic stem cell transplantation, mesenchymal stem cell therapy, chimeric antigen receptor-T cell therapy, natural killer cell therapy, and regulatory T cell therapy, aiming to provide insights for optimization and clinical implementation of cell therapies.
