Hemoptysis induced by ticagrelor

VernacularTitle:替格瑞洛致咯血
Author: Zhen YE ¹ ; Fuliang LUO ; Shuangshuang MA ; Lun CAI ; Shengkun CAO ; Deyin TONG
Author Information

1. 223800,江苏省宿迁市第一人民医院药学部
Publication Type:Journal Article
Keywords: Hemoptysis; Ticagrelor
From: Adverse Drug Reactions Journal 2017;19(5):387-388
CountryChina
Language:Chinese
Abstract: A 70-year-old male patient received ticagrelor 90 mg twice daily and aspirin 100 mg once daily as dual antiplatelet therapy after operation for coronary stent implanting. On day 2 of treatment,he developed traces of blood in sputum. The hemoptysis became worse and times became more after that. On day 42,the patient developed massive hemoptysis about 100 ml. Ticagrelor was discontinued by himself. The patient then was given oxygen inhalation,expectorant drug and hemostatic agents. Anticoagulant therapy was adjusted for the combined use of clopidogrel 75 mg once daily and aspirin 100 mg once daily. On day 4 of the ticagrelor withdrawal,the amount of hemoptysis was obviously reduced. On day 7,the hemoptysis ceased.