Temporal trends and attributable risk factors of chronic kidney disease burden in Fujian Province, 1990-2019
10.3760/cma.j.cn112338-20240516-00280
- VernacularTitle:福建省1990-2019年慢性肾脏病疾病负担的时间趋势和归因危险因素分析
- Author:
Xiuquan LIN
1
;
Xiaoru LIN
;
Chenglin YANG
;
Xinyu WANG
;
Jiang OUYANG
;
Qing GUAN
;
Shaofen HUANG
;
Yanrong YIN
;
Dong LIANG
;
Wenling ZHONG
Author Information
1. 福建省疾病预防控制中心慢性病防治研究室，福州 350000
- Publication Type:Journal Article
- Keywords:
Chronic kidney disease;
Disease burden;
Age-period-cohort model;
Risk factors
- From:
Chinese Journal of Epidemiology
2025;46(1):57-64
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the burden of chronic kidney disease (CKD) and its risk factors in Fujian Province during 1990-2019.Methods:Based on the Global Burden of Disease Study 2019, the incidence rate, mortality rate and disability-adjusted life years (DALYs) of CKD in Fujian from 1990 to 2019 were calculated. An age-period-cohort model was used to estimate the effects of age, period, and cohort on age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized DALY rate (ASDR) of CKD. Comparative risk assessment theory was used to calculate the potential attributable DALYs due to risk factors.Results:In 2019, the ASIR of CKD in Fujian exceeded the national average. The ASIR of CKD showed an increasing trend from 1990 to 2019, but the ASMR and ASDR of CKD exhibited decreasing trends during the same period. In 2019, the ASIR of CKD was higher in women than in men, while the ASMR and ASDR were higher in men than in women. Age-period-cohort analysis indicated that ASIR, ASMR, and ASDR of CKD increased with age. The period effect for ASIR decreased first before increase, while the period effect for ASMR and ASDR displayed fluctuating trends. The cohort effect showed an upward trajectory for ASIR, but a stable status before downward trajectories for ASMR and ASDR. Compared with 1990, except the increase in the ASDR of CKD attributed to high BMI and high temperatures, the ASDR of CKD attributed to other risk factors all showed decreases in 2019. However, the ASDR attributed to high sodium intake remained higher compared with the global average.Conclusion:The burden of CKD remains heavy in Fujian, and it is necessary to reduce the attributable risk factors, such as high sodium intake and high BMI, to address this problem.
