Research progress on the treatment of acute respiratory distress syndrome by titrating positve expiratory end pressure through transpulmonary pressure
10.3760/cma.j.issn.1673-4912.2025.08.010
- VernacularTitle:通过跨肺压滴定呼气末正压在治疗急性呼吸窘迫综合征中的研究进展
- Author:
Yan LI
1
;
Jiujun LI
1
Author Information
1. 中国医科大学附属盛京医院儿内科，沈阳 110004
- Publication Type:Journal Article
- Keywords:
Transpulmonary pressure;
Positve expiratory end pressure;
Esophageal pressure;
Intrathoracic pressure
- From:
Chinese Pediatric Emergency Medicine
2025;32(8):610-613
- CountryChina
- Language:Chinese
-
Abstract:
Acute respiratory distress syndrome（ARDS）is a common life-threatening disease with high mortality caused by inflammatory disorder and oxidative stress in intensive care unit.Respiratory support is the most important clinical treatment.Transpulmonary pressure can accurately reflect the retraction force of the surface of the pleural cavity against the lung tissue，and is the actual stress acting on the lung.Although there are studies suggesting that the measurement of transpulmonary pressure can guide positve expiratory end pressure titration in ARDS patients,so as to achieve individualized treatment and improve patient oxygenation，its clinical application value is still controversial.This review analyzed the advantages and disadvantages of transpulmonary pressure monitoring，guided the treatment of ARDS，and provided individualized and accurate help for setting ventilator parameters for ARDS patients in clinic.
