Neuroimaging advances in cognitive impairment associated with ischemic heart disease from a heart-brain interaction perspective
10.13929/j.issn.1003-3289.2025.08.002
- VernacularTitle:心脑交互视角下缺血性心脏病认知功能障碍的影像学研究
- Author:
Jie LU
1
;
Xiaohu LI
Author Information
1. 首都医科大学宣武医院放射与核医学科,北京 100053;磁共振成像脑信息学北京市重点实验室,北京 100053
- Publication Type:Journal Article
- Keywords:
myocardial ischemia;
cognition disorders;
magnetic resonance imaging;
positron-emission tomography
- From:
Chinese Journal of Medical Imaging Technology
2025;41(8):1200-1206
- CountryChina
- Language:Chinese
-
Abstract:
The heart-brain axis is the core of human homeostasis regulation,and its functional abnormalities are the key link connecting cardiovascular and nervous system disorders.Ischemic heart disease(IHD)not only impairs the structure and function of myocardium,but also causes cognitive dysfunction through the disorder of heart-brain interaction pathways.Its essence lies in the multi-dimensional damage to the structure and function of brain caused by the pathological state of the heart.Multimodal neuroimaging techniques have important value for studying mechanisms of heart-brain interaction.MRI and PET can accurately assess pathological changes such as brain structural and functional damage,metabolic abnormalities and neuroinflammation.The neuroimaging for early identification,formulating heart-brain co-treatment strategies and improving the management level of IHD related cognitive dysfunction were reviewed in this article.
