Correlations of gut microbiota and short-chain fatty acids with chronic spontaneous urticaria
- VernacularTitle:肠道菌群及短链脂肪酸与慢性自发性荨麻疹相关性研究进展
- Author:
Enze LI
1
;
Lu CHEN
;
Chuqiao ZHANG
;
Yuxu YAO
;
Qingqing JIAO
;
Jiang JI
Author Information
- Publication Type:Journal Article
- Keywords: Urticaria; Chronic spontaneous urticaria; Gut microbiota; Short-chain fatty acids
- From: Chinese Journal of Dermatology 2025;58(6):577-581
- CountryChina
- Language:Chinese
- Abstract: Autoimmunity and the activation of immune cells are closely related to the occurrence of chronic spontaneous urticaria, while the gut microbiota participates in multiple physiological activities including the regulation of the host's immunity. Gut microbiota in patients with chronic spontaneous urticaria has unique structural composition and metabolic features. Gut microbiota imbalance and secondary short-chain fatty acid deficiency may be important causes for the occurrence of the disease and aggravation of inflammation. Studies have shown that probiotics can improve the clinical manifestations of patients with urticaria. This review summarizes the research progress in the correlations of gut microbiota and short-chain fatty acids with chronic spontaneous urticaria.
