Latent profile analysis and influencing factors of self-management ability in patients with metabolic-associated fatty liver disease
10.3760/cma.j.cn115624-20250414-00322
- VernacularTitle:代谢相关脂肪性肝病患者自我管理能力的潜在剖面分析及影响因素
- Author:
Yingfen ZHANG
1
;
Feifei YU
;
Er CHEN
;
Meiling LIU
;
Ruiming LIANG
;
Suijuan PENG
;
Huiling LIANG
;
Yafang HE
Author Information
1. 广东省中山大学医学院·中山大学附属第一医院特需医疗中心门诊，广州510080
- Publication Type:Journal Article
- Keywords:
Fatty liver;
Metabolism;
Latent profile analysis;
Cross-sectional study;
Self-management
- From:
Chinese Journal of Health Management
2025;19(11):915-922
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the latent profile characteristics of self-management ability in patients with metabolic-associated fatty liver disease (MAFLD) and explore its influencing factors.Methods:This was a cross-sectional study. A total of 311 patients with metabolic-associated fatty liver disease (MAFLD) were selected from the First Affiliated Hospital of Sun Yat-sen University (including those receiving treatment and undergoing physical examinations) between August and October 2024. Data were collected using a general information questionnaire, the self-management Scale for Patients with Non-Alcoholic Fatty Liver Disease, and the Social Support Rating Scale. After excluding 51 patients due to incomplete questionnaire responses or logical inconsistencies, 260 patients were finally included in the analysis. Latent profile analysis was used to identify potential categories of patients′ self-management abilities. With the latent categories as the dependent variable and items with P<0.05 in univariate analysis as independent variables, a multivariate logistic regression analysis (with the "poor self-management group" as the reference group) was performed to explore the influencing factors. Results:Among the 260 participants included in the study, three potential categories of self-management behaviors were finally identified, namely the active self-management group with 106 cases (40.8%), the moderate self-management group with 118 cases (45.4%), and the passive self-management group with 36 cases (13.8%).Results of multivariate logistic regression analysis showed that, compared with the passive self-management group:Patients who resided in rural areas ( OR=0.130, 95% CI: 0.040-0.420), often stayed up late ( OR=0.200, 95% CI: 0.060-0.590), or had an average daily sleep duration of≤5 hours ( OR=0.160, 95% CI: 0.050-0.510) had a significantly lower probability of belonging to the "active self-management group";In contrast, patients with an education level of senior high school or above ( OR=7.530, 95% CI: 1.740-34.160) or a higher total score of social support ( OR=1.120, 95% CI: 1.030-1.210) had a significantly higher probability of being in the "active self-management group" (all P<0.05). Conclusion:There is heterogeneity in self-management ability among patients with metabolic associated fatty liver disease (MAFLD). Residential area, educational level, frequency of staying up late, average daily sleep duration, and social support are influencing factors of patients′ self-management ability.
