Sleep duration and risk of cardiovascular and metabolic comorbidity in middle-aged and elderly people: a cohort study
10.3760/cma.j.cn115624-20250215-00124
- VernacularTitle:中老年人群睡眠时长与心血管代谢性共病发病风险关系的队列研究
- Author:
Jiahong YIN
1
;
Ying GAO
1
;
Junfang YOU
1
;
Jie CHENG
1
;
Weilu CHEN
1
;
Li LIU
1
;
Qing ZHANG
1
;
Haiyan SU
1
Author Information
1. 天津医科大学总医院健康管理中心 天津市健康管理与促进研究所，天津 300070
- Publication Type:Journal Article
- Keywords:
Cardiovascular Diseases;
Metabolic Diseases;
Comorbidity;
Sleep duration;
Cohort study;
Middle-aged and elderly people
- From:
Chinese Journal of Health Management
2025;19(7):523-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the relationship between sleep duration and cardiovascular and metabolic comorbidities (CMM) in middle-aged and elderly people in China.Methods:This study was a prospective cohort study, based on the data of China Health and Retirement Tracing Survey (CHARLS) from 2011 to 2015, and included middle-aged and elderly people aged≥45 years in the cohort study. Age, gender, marital status, residence, education, smoking status, alcohol status, body mass index, history of diabetes, history of dyslipidemia, history of hypertension, history of stroke, history of heart disease, history of mental illness, depression scale score were collected. Multivariate logistic regression was used to analyze the association between daily sleep duration and the risk of CMM onset and to construct four models with stepwise adjusted covariates. A stratified analysis was established based on demographic factors, lifestyle factors, metabolic factors, cardiovascular and cerebrovascular factors, and psychological factors. Meanwhile, a subgroup analysis was established according to different combinations of cardiovascular and metabolic diseases to explore the association between sleep length and the risk of CMM in different populations.Results:A total of 297 (4.4%) of the 6 788 included participants experienced CMM. In the multivariate logistic regression, the RR value (95% CI) for the risk of CMM for>9 h was 1.99 (1.86-2.08) and 1.78 (1.64-1.92), respectively (all P<0.001). The stratified analysis showed that the risk of CMM incidence between sleep duration<7 h and>9 h was associated in people with different age, sex, residence, smoking status, drinking status, body mass index, hypertension, hypertension, diabetes, heart disease, stroke, dyslipidemia, and depression (all P<0.05). Subgroup analysis showed that sleep duration<7 h with both diabetes, heart disease and stroke had the highest risk of CMM ( RR=1.95, 95% CI: 1.65-2.14). Conclusion:In the middle-aged and elderly group in China, there is a U-shaped association between sleep duration and CMM, that is, insufficient or too long sleep duration throughout the day is related to the increased risk of CMM.
