Correlation between emphysema and coronary artery calcification in health screening population
10.3760/cma.j.cn115624-20240920-00764
- VernacularTitle:健康体检人群肺气肿与冠状动脉钙化的相关性
- Author:
He YU
1
;
Mingxia WU
1
;
Zongtao CHEN
1
;
Jie ZHOU
1
Author Information
1. 陆军军医大学第一附属医院健康管理科，重庆 400038
- Publication Type:Journal Article
- Keywords:
Pulmonary emphysema;
Coronary artery calcification;
Health screening;
Tomography scanners, X-ray computed;
Risk factors
- From:
Chinese Journal of Health Management
2025;19(1):25-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation between pulmonary emphysema and coronary artery calcification (CAC) in a health screening population.Methods:This retrospective case-control study consecutively selected 55 762 individuals who underwent chest low-dose chest CT (LDCT) screening at the Health Management Center of Southwest Hospital from January 2019 to December 2023. Demographic data, history of chronic diseases, anthropometric measurements, laboratory indicators, LDCT and pulmonary function test results were collected. Exclusion criteria included age<40 years at baseline, a history of coronary heart disease, LDCT suspected coronary artery stent placement, incomplete baseline data, and duplicate examinations. Logistic regression models were used to analyze the association between pulmonary emphysema and CAC.Results:A total of 33 069 individuals were included, with a mean age of 52 (47, 58) years old. Among them, 20 114 (60.8%) were male, 2 967 (9.0%) had pulmonary emphysema, and 4 156 (12.6%) had coronary artery calcification. The proportion of CAC in patients with emphysema was higher than in those without (23.5% vs 11.5%; χ2=351.805, P<0.001). After adjusting for confounding factors, the risk of CAC remained significantly higher in patients with emphysema [ OR=1.239 (95% CI: 1.113-1.379), P<0.001]. Conclusion:Pulmonary emphysema was one of the independent risk factors for coronary artery calcification in a health screening population.
