One case of respiratory failure caused by occupational acute acetonitrile poisoning
10.3760/cma.j.cn121094-20240813-00377
- VernacularTitle:职业性急性乙腈中毒所致呼吸衰竭1例
- Author:
Ruikai SHANG
1
;
Hongyu LIU
;
Qiaoxin TIAN
;
Yuru LIU
;
Xiangdong JIAN
Author Information
1. 山东大学公共卫生学院劳动卫生与环境卫生学系，济南 250014
- Publication Type:Journal Article
- Keywords:
Poisoning;
Acetonitrile;
Toxic encephalopathy;
Occupational exposure;
Respiratory failure
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2025;43(11):859-861
- CountryChina
- Language:Chinese
-
Abstract:
This article analyzes the treatment process of a patient with respiratory failure caused by occupational acute acetonitrile poisoning. Due to operational errors, the patient's body was sprayed with a large amount of acetonitrile liquid, leading to the absorption of acetonitrile through the skin and resulting in acute poisoning. The clinical manifestations were nervous system and respiratory system damage, accompanied by severe lactic acidosis. After active comprehensive treatments such as tracheal intubation, mechanical ventilation, continuous renal replacement therapy (CRRT) , and glucocorticoids, the patient basically recovered. The treatment process of this patient indicates that early identification and correct first aid of acetonitrile poisoning are the keys to improving prognosis and can provide a reference for the handling of similar clinical cases.
