Research progress on DNA methylation as a diagnostic biomarker for malignant mesothelioma
10.3760/cma.j.cn121094-20240417-00170
- VernacularTitle:DNA甲基化作为恶性间皮瘤诊断标志物的研究进展
- Author:
Lin CUI
1
;
Xinliang ZHENG
;
Min ZHANG
Author Information
1. 杭州医学院公共卫生学院，杭州 310000
- Publication Type:Journal Article
- Keywords:
Mesothelioma;
DNA Methylation;
Malignant mesothelioma;
Diagnosis;
Biomarkers;
Diagnostic markers
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2025;43(7):547-551
- CountryChina
- Language:Chinese
-
Abstract:
Malignant mesothelioma is a rare tumor that is highly correlated with asbestos exposure. Due to the insidious early symptoms, mesothelioma is usually diagnosed in the advanced stages of the disease. Therefore, there is an urgent need for some early detection biomarkers to assist in the diagnosis of mesothelioma. The detection of DNA methylation can be one of the new research directions. This article provides a comprehensive discussion on the research progress of DNA methylation in malignant mesothelioma, including genes that can serve as diagnostic markers for malignant mesothelioma and the current problems in clinical application. It also provides new insights for future research directions using DNA methylation as a diagnostic marker for mesothelioma.
