A case of rhabdomyolysis caused by acute thiamethoxam poisoning

VernacularTitle:急性噻虫嗪中毒致横纹肌溶解症1例
Author: Benhe WU ¹ ; Min XU ¹ ; Mingfeng LU ¹ ; Runmin ZHAO ¹
Author Information

1. 扬州大学附属苏北人民医院急诊医学科，扬州　225001
Publication Type:Journal Article
Keywords: Poisoning; Thiamethoxam; Rhabdomyolysis
From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2025;43(7):536-538
CountryChina
Language:Chinese
Abstract: Thiamethoxam belongs to the second-generation neonicotinoid insecticides, mainly acting on nicotinic acetylcholine receptors (nAChR) . Severe poisoning cases can lead to respiratory failure, shock, and even death. There are relatively few reports on thiamethoxam poisoning, and few literature reports on concurrent rhabdomyolysis cases have been found so far. This article reviews the treatment process of a case of oral thiamethoxam poisoning. The patient developed mild rhabdomyolysis (CK: 1581 U/l) and renal dysfunction (creatinine: 127 μmol/L) immediately after taking the medication, reaching its peak on the second day (CK: 16329 U/l) . After active treatment (such as Blood purification, drainage, gastrointestinal decompression and organ support) , the symptoms of rhabdosis gradually improved and the patient was discharged. It is suggested that when treating thiamethoxam poisoning, the occurrence of rhabdomyolysis syndrome should be concerned.