Analysis of symptom burden and its influencing factors in patients with spastic dysfunction after stroke
10.3760/cma.j.cn114798-20250609-00587
- VernacularTitle:卒中后痉挛性功能障碍患者的症状负担及其关联因素分析
- Author:
Wenfang JIANG
1
;
Jing MA
1
;
Luo JIA
1
Author Information
1. 绍兴市中医院 浙江中医药大学附属绍兴中医院神经内科，绍兴312000
- Publication Type:Journal Article
- Keywords:
Stroke;
Dysfunction;
Spasm;
Symptom burden
- From:
Chinese Journal of General Practitioners
2025;24(9):1122-1127
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the present situation of symptom burden in patients with spastic dysfunction after stroke and to analyze its influencing factors.Methods:This was a cross-sectional study. Patients with spastic dysfunction after stroke who were treated in the Department of Neurology, Shaoxing Hospital of Traditional Chinese Medicine, from September 2021 to September 2023 were enrolled. General clinical data on the patients was obtained via questionnaire surveys. The corresponding scales were used to evaluate both the symptom burden experienced by the patients (which included 6 dimensions: physiological function, cognitive function, psychological function, pain manifestation, motor abnormalities and speech ability) and their severity of spasms. Pearson correlation analysis was used to assess the correlation between the symptom burden of patients and the severity of spasms. The associated factors of symptom burden in patients with spastic dysfunction following a stroke were analyzed using a multiple linear regression model.Results:A total of 147 patients with spastic dysfunction after stroke were included with an average age of (65.15±7.15) years old. There were 78 males (53.06%). The overall symptom burden of the enrolled patients was high ((38.42±5.78) points), with the burden of physiological function being the highest, followed by the burden of psychological function. The clinical spasticity index score of the enrolled patients was (12.26±3.14) points. Pearson correlation analysis showed that the symptom burden score of patients with spastic dysfunction after stroke was positively correlated with the clinical spasm index score ( r=0.438, P<0.001). The results of multiple linear regression analysis showed that age, disease duration, monthly family income, and the score of the Mental Health Inventory-5 (MHI-5) were independent associated factors for symptom burden in patients with spastic dysfunction after stroke (all P<0.05). Conclusions:Patients with spastic dysfunction after stroke have a high symptom, especially in physiological and psychological functions. Age, disease duration, economic status, and mental health status are independent associated factors for the symptom burden in such patients.
