Medication adherence and associated factors among elderly patients with comorbidities in the General Practice Department of Zhoukou Central Hospital
10.3760/cma.j.cn114798-20250711-00859
- VernacularTitle:周口市中心医院全科医学科老年共病患者服药依从性及其关联因素分析
- Author:
Juan KONG
1
;
Hao WANG
;
Xiaoyan LI
;
Mi YAO
Author Information
1. 周口市中心医院全科医学科,周口 466000
- Publication Type:Journal Article
- Keywords:
Comorbidity;
Aged;
Drug compliance
- From:
Chinese Journal of General Practitioners
2025;24(9):1070-1074
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess medication adherence and identify independent associated factors among elderly patients with multimorbidity attending the Department of General Practice at Zhoukou Central Hospital.Methods:This cross-sectional study enrolled 380 elderly patients with multimorbidity through convenience and snowball sampling between March 2023 and March 2024. Face-to-face interviews were conducted with the subjects through community general practice clinics and resident group discussions. The survey covered the subjects′ general clinical information and medication adherence. Medication adherence was assessed using the Chinese version of the 8-item Morisky Medication Adherence Scale (MMAS-8). Multivariate logistic regression analyzed independent factors of medication adherence in elderly patients with multimorbidity.Results:A total of 380 patients were included in the analysis, with an mean age of (71.57±7.58) years, and 211 (55.5%) were males. Only 50 patients (13.2%) demonstrated good adherence. Multivariate logistic regression revealed lower adherence in ages 60-69 vs.≥80 ( OR=4.595, 95% CI:1.730-12.207, P=0.002), higher adherence in high school and above education vs. primary/illiterate ( OR=0.278, 95% CI:0.082-0.944, P=0.040), reduced adherence with increased household responsibility ( OR=3.684, 95% CI:1.799-7.543, P<0.001). Conclusions:Medication adherence was suboptimal among elderly patients with multimorbidity attending the Department of General Practice at Zhoukou Central Hospital. Age, education, and household responsibility burden were independent predictors for medication adherence.