Research progress on the association between apolipoprotein B/apolipoprotein A1 ratio and pan-vascular diseases
10.3760/cma.j.cn114798-20240624-00561
- VernacularTitle:载脂蛋白B/载脂蛋白A1比值与泛血管疾病关联的研究进展
- Author:
Baiju WANG
1
;
Han LI
1
;
Lei LIU
1
;
Hanwen CHEN
1
Author Information
1. 济宁医学院附属医院全科医学科，济宁 272029
- Publication Type:Journal Article
- Keywords:
Atherosclerosis;
Apolipoproteins A;
Apolipoproteins B;
Pan-vascular disease
- From:
Chinese Journal of General Practitioners
2025;24(4):496-500
- CountryChina
- Language:Chinese
-
Abstract:
Systemic vascular diseases characterized by a common pathological feature of atherosclerosis are referred to as pan-vascular disease, the incidence and mortality of which are increasing currently. Apolipoproteins are closely related to the occurrence of atherosclerosis due to their genetic polymorphism, and expected to become new biomarkers for prediction and intervention of the disease. This article reviews the research progress on the biological functions of apolipoproteins, and the association of the apolipoprotein B (ApoB)/apolipoprotein A1 (ApoA1) ratio with the pathogenesis and progress of atherosclerosis. Understanding the ApoB/ApoA1 ratio in different populations with pan-vascular diseases and its effects on different interventions will be conducive to precise and personalized disease management, and to improve clinical outcomes and the quality of life of patients.
