Clinical characteristics and related factors of cognition disorders in elderly patients with hypertension
10.3760/cma.j.cn114798-20240724-00635
- VernacularTitle:老年高血压患者合并认知障碍的临床特征及其关联因素分析
- Author:
Jinling GU
1
;
Lingling PAN
1
;
Shishi WEN
1
;
Qianqian SUN
1
;
Xueyan HAN
1
;
Huan CHEN
1
;
Zhizhen LYU
1
;
Hao XUE
1
;
Zifang YIN
1
Author Information
1. 解放军总医院第六医学中心心血管病医学部，北京100037
- Publication Type:Journal Article
- Keywords:
Hypertension;
Aged;
Cognition disorders
- From:
Chinese Journal of General Practitioners
2025;24(1):70-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical characteristics and related factors of cognition disorders in elderly hypertensive patients.Methods:It was a cross-sectional study. A total of 612 hypertensive patients with the age of (69.06±6.58) years (median 68.00 years) admitted in the Department of Cardiology, General Hospital of Chinese People′s Liberation Army from October 2022 to April 2024 were enrolled. The demographic and clinical data were collected, the cognition status was assessed with Mini-Mental State Examination (MMSE) at admission. The related factors of cognition disorders were analyzed with univariate and multivariate logistic regression.Results:The results showed that female hypertensive patients and those with older age, lower education, higher fasting blood glucose (FBG) and diabetes mellitus, higher low-density lipoprotein cholesterol (LDL-C) level, higher systolic blood pressure (SBP) and more cardiovascular comorbidities were likely to have cognition disorders (all P<0.05). Multivariate logistic regression analysis showed that smoking history, elevated SBP, elevated heart rate, elevated FBG, and elevated LDL-C were independent risk factors for cognition disorders in elderly hypertensive patients,while higher education level was an independent protective factor (all P<0.05). Conclusion:Smoking, increased SBP, increased heart rate, increased FBG, increased LDL-C and lower education level are independently associated with cognition disorders in elderly hypertensive patients.
